How to Titrate with Compounded Semaglutide

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Here’s what we’ll cover in this blog post:

  • How to measure doses on your syringe
  • How to draw up the solution
  • How to inject Compounded Semaglutide
  • What to do if you’d like to adjust your dose

If you’re just getting started with Compounded Semaglutide, you’ll probably have a lot of questions about your dosing schedule: How do I stay on top of my weekly doses? Why do my weekly doses change? What if I want to stick with the dose I’m on now?

Even if this is your first time using a self-injectable medication, keeping up with your Compounded Semaglutide doses is no problem—especially with help from your AgelessRx experts.

Here’s everything you need to know about how to titrate with Compounded Semaglutide.

How to Measure Doses on Your Syringe

Some of the first things you’ll notice about your Compounded Semaglutide prescription are the needles and syringes that come with each refill. Compounded Semaglutide is delivered using traditional injection methods, which means you’ll have to carefully measure out the solution in the syringe before you inject.

You’ll also notice that your weekly doses are measured in milligrams (mgs) to units. You want to pay attention to how many units are in your weekly dose.

The labels on the side of your syringe indicate measurements of units. The larger lines each represent 10 units, up to a total of 100. The smaller lines in between each larger line represent 1 unit each. 

If your weekly dose calls for 20 units, simply draw the solution up to the line that reads “20.”

If your weekly dose calls for a measurement like 25 or 35 units, pay close attention to the markers between the large lines when drawing up your dose. There may be even smaller measurements on the syringe that are more difficult to see. Use the same strategy as above and count each unit carefully before you inject to make sure you receive the correct dose.

When learning how to titrate with Compounded Semaglutide, you’ll also notice your weekly units go up each month. By starting with a lower dose, you’re giving your body a chance to acclimate to the medication. That way, any potential side effects won’t be exacerbated by higher doses. This makes it easier for your body to tolerate higher doses, leading up to your target dose.

How to Draw Your Solution

Once you understand how to measure doses on your syringe, you can begin drawing up your dose

Before you start, grab your vial of solution and clean the top with an alcohol wipe. Be sure not to touch the top of the vial once it’s been cleaned. Your current dose will always be displayed on your vial. Use this as a reminder before you begin.

Start by drawing back the plunger of the syringe to the exact measurement of your dose. You’ll need to inject about this much air into the vial to draw your dose.

Next, push the needle into the top of the vial, and flip the vial and syringe over so the plunger is at the bottom. Inject the air into the vial, then pull the plunger back down until the black line on the inside of the syringe matches your weekly dose.

Once the top of your vial has been pierced, you must discard it after 28 days, even if there’s some solution left over.

How to Administer Your Weekly Injection

Compounded Semaglutide is delivered via subcutaneous injection. That means you’ll inject into a layer of fatty tissue like your abdomen or your thigh.

Start by selecting an area on your body to inject. Keep in mind that you may experience some irritation at the injection site. To avoid further irritation, you should always switch to a new injection site each week.

Next, grip the syringe with your dominant hand and grasp the injection site with your other hand.

If you can grasp at least 2 inches of skin, deliver the injection at a 90° angle with your body (or, straight in). If you can’t grasp at least 2 inches of skin, deliver the injection at a 45° angle. 

Use your wrist to inject the needle into the skin, and press the plunger down slowly until you administer the full dose. Leave the needle in for 5 seconds to ensure there’s no leakage, then carefully remove the needle.

After you’ve administered the injection, discard the needle in an FDA-approved sharps container. Never recap the needle or reuse the syringe once they’ve been used.

Follow Your Titration Schedule

Once you know how to draw and inject your medication, learning how to titrate with Compounded Semaglutide is as simple as following your titration schedule.

The best place to check your weekly dose is on the side of your prescription vial. You can also keep track of your weekly doses on your AgelessRx portal

Keep in mind that your prescribed doses are unique to you and may differ from other sources online. Always follow your doctor-guided titration schedule provided on your prescription vial or in your AgelessRx portal.

What If I Want a Different Titration Schedule?

You should think of your titration as less of a schedule, and more of a guideline to give you the most optimal results while minimizing side effects. 

If you do experience side effects and feel you can’t tolerate another dose increase, let your prescriber know before your next refill. It’s perfectly acceptable to maintain the dose you’re most comfortable with until you’re ready.

On the other hand, you may find that you’re not getting the results you expected at the max dose. In this case, you can also talk to your prescriber about potentially increasing your dose.
Finding your goldilocks dose for Compounded Semaglutide can be tricky, but finding the dose that’s just right for you is our primary goal. If you have any questions about your Compounded Semaglutide titration, please don’t hesitate to contact us. Your dedicated AgelessRx support team is happy to help you through every step of the process, so you have the safest and most rewarding outcomes.


Note: The above statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.